Things that seem like they should work often don't. Just ask Perry Wilson.
And even the most predictable cases of AKI are resistant to intervention. Look at bypass surgery. We know days in advance the time and place the AKI will occur and despite that foreknowledge, like Cassandra, we are powerless to prevent the AKI. Same with contrast administration (or not). Same with AAA surgery. We have been unable to meaningfully reduce the rate of AKI in any clinical circumstance.
AKI is a tough nut to crack.
So when I read about this guy, Mustafa Suleyman (Twitter), telling the public that,
"There are around 1,000 people a month dying needlessly. This is a huge hidden killer. It costs more than breast cancer care in the UK and [AKI] is super simple to prevent."I'm insulted, like we must be idiots that we haven't fixed this yet. And thank-god the computer scientists are here from Google to finally cure AKI for us.
Turns out the National Health Service is implementing a system at The Royal free Hospital to speed alerts to doctors so they can react quickly to signals of acute kidney injury. The headlines being generated from this project are amazing:
The company providing artificial intelligence is DeepMind, a Google company. The product that detects AKI early enough to avoid it is Streams.
Maybe we should excuse the visionary of an artificial intelligence company. The medical director of the Royal Free should be a bit less grandiose and more evidence based. What did he have to say?
Stephen Powis, medical director at the Royal Free said, “We know that a quarter of deaths from acute kidney injury are preventable if clinicians are able to intervene earlier and more effectively.”
@ddfirl @kidney_boy NCEPOD report says up to 30% preventable https://t.co/e6hbpIqKQY ref: prospective observ'n data: https://t.co/0HjUx0rTUM pic.twitter.com/SIQqzrx20V— Benjamin Stewart (@drbstewart) November 23, 2016
Nothing prospective. Nothing to justify the certainty of Dr. Powis. The 25% comes from a report produced by NCEPOD called Adding Insult to Injury. The report attempted to analyze all of the deaths for 3 months in 2007 due to AKI. They failed to capture surgical patients and they did not get the records on 40% of the cases they requested.
As part of this examination of the failures they asked experts that reviewed the case files if the AKI was avoidable and they said yes it was in 14% of the cases. I'm sorry, but the distance between a reviewer believing an episode is avoidable and an AKI case actually being avoidable is more than a casual step, let's call it a major leap. Remember that reviewers were only reviewing patients with mortal outcomes. Given that, the reviewers knew of the subpar outcome, I'm not surprised the reviewers found lots of substandard care:
I believe the Deep Mind people have this type of model of AKI:
I think the correct model of AKI is more like this:
I look forward to seeing the results of this project and hope that they are measuring the outcomes and plan to publish their prospective and interventional data.